Depo provera

Dizziness, headaches, irregular periods and breakthrough bleeding, nervousness. Hepatic Impairment depo-provera Sterile Aqueous Suspension should not be used depo by women depo with significant liver disease and should be discontinued if jaundice or provera disturbances of provera liver function occur see precautions. Ask friends, family members, or your partner to provera remind you. But the depo risk of provera pregnancy is depo much lower in provera women who return every 3 months for their injections. A healthcare provider will give you this provera injection once every 3 months (12 to depo 14 weeks). This medication was approved by the Food and Drug Administration (FDA) in 1992 provera and is depo manufactured by Pfizer, Inc. The provera longer you wait between injections, the more likely you are depo to get pregnant. Carcinogenesis, Mutagenesis, Impairment of Fertility Long-term intramuscular depo administration of Medroxyprogesterone depo acetate (MPA) provera has depo provera side effects been shown to produce mammary tumors in beagle dogs. Depo-Provera provera and depo-subQ provera 104 injections are used as contraception to prevent pregnancy. Also use a condom every time you have vaginal sex. Other side effects of Depo-Provera usually decrease or stop within the first few provera side effects months. Using condoms will decrease your risk of a sexually transmitted infection. T3 uptake provera values may provera decrease. Because of this, the Food and Drug Administration added strong warnings to the injection packaging cautioning that Depo-Provera and Depo-SubQ Provera 104 shouldn't be used for longer than two years. Depo-Provera starts provera to work provera as birth control provera immediately after the first shot, if you get it within the first 5 days of your menstrual period. Bleeding from your nipples, excessive weight gain or fluid retention before menstruation. Renal Impairment The effect depo of renal impairment on depo-provera pharmacokinetics has not been studied. From Women's Health Resources Featured Centers Health Solutions From Our Sponsors Report Problems to the Food and Drug Administration You are encouraged to report negative side effects of prescription drugs to the FDA. Tell your doctor if this bleeding continues or is very depo heavy. Whether this will provide protection from endometrial carcinoma has not been clearly established. Org: "Depo-Provera: An Injectable Contraceptive." MedlinePlus: "Medroxyprogesterone Injection." Sexuality Information and Education Council of the United States: "Talk About Sex." 2017 WebMD, LLC. F) Sulfobromophthalein and other liver function test values may be increased. Warnings warnings Thromboembolic Disorders The physician should be alert to the earliest manifestations of thrombotic disorder ( thrombophlebitis, cerebrovascular disorder, pulmonary embolism, and retinal thrombosis). (See precautions: Decrease in Bone depo Mineral Density ) Drug Interactions Aminoglutethimide administered concomitantly with Depo-Provera Sterile Aqueous Suspension may significantly depress the serum concentrations of medroxyprogesterone provera acetate. Protein bound iodine and butanol extractable protein bound iodine may increase. This medicine will not protect you from sexually transmitted diseases provera -including HIV and aids. Depo-Provera isn't appropriate for everyone, however. Morphological and biochemical studies of endometrial suggest that 10-13 depo days of a progestin are needed to provide maximal maturation of the endometrium and to eliminate any hyperplastic changes. Interference With Laboratory Tests The use of depo-provera Sterile Aqueous Suspension may change the results of some provera laboratory provera tests, such as coagulation factors, lipids, glucose tolerance, and binding proteins. If you get your first shot provera within the first 7 days after the start of your period, youre protected from pregnancy right away. Depo-Provera ( medroxyprogesterone ) is a form of progesterone, a female hormone that prevents ovulation (the release of an egg from an ovary). This medicine may also increase the chance of developing blood clots that move to your lungs or brain. Does the shot protect against STDs? Copyright Cerner Multum, Inc. Retinal thrombosis and optic neuritis. Known sensitivity to Depo-Provera (medroxyprogesterone acetate or any of its other ingredients). Decreases menstrual cramps and pain, lessens menstrual blood flow, and in some cases stops menstruation. C) Sex-hormone binding globulin concentrations are decreased. Tell your doctor if you have ever had: light depo or irregular menstrual periods; risk factors for osteoporosis (such as low bone depo mineral density, a family history depo provera side effects of osteoporosis, drinking large amounts of alcohol, or if you smoke depo a breast. Interference with Laboratory Tests The use of Depo-Provera Sterile Aqueous Suspension may change the results of some laboratory tests, such as coagulation factors, lipids, glucose tolerance, and binding proteins. How depo does the birth control shot work? Tell your doctor about all your other medicines, especially: This list is not complete. Talk to your doctor about these risks. Brand Names: Depo-Provera, depo depo-subQ provera 104, medically reviewed on Aug 13, 2018, what is Depo-Provera? Both increases and decreases in total cholesterol, triglycerides, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol have been observed in studies. Can Any Woman Use Depo-Provera? Medroxyprogesterone can decrease the calcium stored in your bones, which may cause bone loss ( osteoporosis ) when the medicine is used over long periods of time. It also works by making cervical mucus thicker. Your health care provider might recommend Depo-Provera if: You don't provera want to take a birth control pill every day. The mechanism of this decrease is obscure. Caution should be exercised when medroxyprogesterone acetate is administered to a nursing woman. Depo-Provera is 99 percent effective at preventing pregnancy. Generic Name: medroxyprogesterone acetate, dosage Form: injection, suspension, medically reviewed on Aug 1, 2017, show On This Page. Prolonged Use The effect of prolonged use of depo-provera Sterile Aqueous Suspension at the recommended doses on pituitary, ovarian, provera adrenal, hepatic, and uterine function is not known. In fact, some studies suggest that hormonal contraceptives such as Depo-Provera might increase a woman's risk of chlamydia and HIV. Tell your doctor if you or anyone in your family has ever had osteoporosis, breast cancer, or diabetes before taking this medication. Medroxyprogesterone acetate was not mutagenic in a battery provera of in vitro or in vivo genetic toxicity assays. Seek emergency medical attention or call the Poison Help line. The physical examination, however, may be deferred until after initiation of depo depo provera side effects provera if requested by the woman and judged appropriate by the clinician. Indications AND uses, adjunctive therapy and palliative treatment of inoperable, recurrent, and metastatic endometrial or renal carcinoma. How is Depo-Provera Supplied Depo-Provera Sterile Aqueous Suspension is available as 400 mg/mL.5 mL vials. Laboratory test interactions The pathologist should be advised of progestin therapy when relevant specimens are submitted. Medroxyprogesterone can decrease the calcium stored in your bones, which may cause bone loss (osteoporosis) when the medicine is used over long periods of time. Medroxyprogesterone acetate may have cortisol-like glucocorticoid activity and provide negative feedback to the hypothalamus or pituitary. Its OK depo for most women. You may be more likely to have a broken bone if your bones get weak from calcium loss, especially after menopause. Investigations change in weight (increase or decrease) depo Hepatobiliary Disorders Skin And Subcutaneous Tissue Disorders skin sensitivity reactions consisting of urticaria, pruritus, edema provera and generalized rash acne, alopecia and hirsutism rash (allergic) with and without pruritis Immune System Disorders Gastrointestinal Disorders nausea Endocrine. Among various benefits, Depo-Provera: Doesn't require depo daily action, eliminates the need provera to interrupt sex for contraception. Backup birth control isn't necessary after subsequent injections as long as they're given on schedule. Depo-Provera is the brand name of the drug medroxyprogesterone, which is an injection used to prevent pregnancy. The shot is really good at preventing pregnancy, but it wont protect you from sexually transmitted infections. You can become depo pregnant as soon as 3 to 4 months after your last shot. Your doctor will need to see you on a regular basis while you are using Depo-Provera. Overview, depo-Provera is a well-known brand name for medroxyprogesterone acetate, a contraceptive injection for women that contains the hormone progestin. Contraindications Active thrombophlebitis, or current or past history of thromboembolic disorders, or cerebral vascular disease Known sensitivity to depo-provera (medroxyprogesterone acetate or any of its other ingredients). Pregnancy Teratogenic Effects It is not known whether medroxyprogesterone acetate can cause fetal harm when administered to a pregnant woman. Principal display panel -.5 mL Vial Label.5 mL Vial NDC Depo-Provera medroxyprogesterone acetate injectable depo suspension, USP 1,000 mg/2.5 provera mL (400 mg/mL) For IM use only Rx only principal display panel -.5 mL Vial Carton NDC.5 mL Vial Depo-Provera medroxyprogesterone. Risks, in a year of typical use, an estimated 6 out of 100 women using Depo-Provera will get pregnant. Multi-Dose Use Multi-dose use of depo-provera Sterile Aqueous Suspension from a single vial requires special care to avoid contamination. Depo-Provera is effective at preventing pregnancy, but it doesn't protect you from sexually transmitted diseases. The following laboratory tests may be affected by progestins including Depo-Provera Sterile Aqueous Suspension: a) Plasma and urinary steroid levels are decreased (e.g. Add it to whatever calendar you use on a daily basis. When necessary, pH was adjusted with sodium depo hydroxide and/or hydrochloric acid. Depo-, provera is a contraceptive method for women. See laboratory test interactions. Why it's done, depo-Provera is used to prevent pregnancy. Further information Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Depo-Provera only for the indication prescribed. Condoms are the only way to help protect yourself from STDs, so using the shot with condoms is the way. Effects On The Hypothalmic-Pituitary-Adrenal Axis Some patients receiving medroxyprogesterone acetate may exhibit suppressed adrenal provera function. Tell your doctor right away if you become pregnant, or if you plan to become pregnant soon after you stop using Depo-Provera. For this reason patients on progestin therapy should be carefully observed. If you've just given birth, your first injection will be done within five days of giving birth, even if you're breast-feeding. Depo-Provera will not protect you from sexually transmitted diseases - including HIV and aids. Breast Cancer, women who have or have had a history of breast cancer should be advised against the use of Depo-Provera, as breast cancer may be hormonally sensitive. See Laboratory Test Interactions. When theres no egg in the tube, pregnancy cant happen. A decrease in glucose tolerance has been observed in a small percentage of patients on estrogen-progestin combination treatment. Thats about every 3 months, or 4 times a year. You want or need to avoid using estrogen. But its not recommended for those who have: It should be used with caution in teens, and by women with osteoporosis because of its relation to bone loss. Depo-Provera side effects Get emergency medical help if you have signs of an allergic reaction depo to Depo-Provera: hives ; difficulty breathing; swelling of your face, lips, tongue, or throat. Dosage AND administration, the suspension is intended for intramuscular administration only, rotating the sites with every injection. The structural formula is: depo-provera for intramuscular injection is available as 400 mg/mL medroxyprogesterone acetate. Loss of calcium may lead to osteoporosis and could increase your risk of a bone fracture. And when the sperm and the egg cant get together, pregnancy cant happen. Depo-Provera and Depo-SubQ Provera 104 have similar benefits and risks. The dosage used may be important in minimizing these adverse effects. Fluid Retention Because progestational drugs may cause some degree of fluid retention, conditions which might be influenced by this condition, such as epilepsy, migraine, asthma, cardiac or renal dysfunction, require careful observation. You might not become pregnant for some time after your last injection of Depo-Provera. If improvement is noted within a few weeks depo or months and the disease appears stabilized, it may be possible to maintain improvement with as little as 400 mg per month. Actions, medroxyprogesterone acetate, administered parenterally in the recommended doses to women with adequate endogenous estrogen, transforms proliferative endometrium into secretory endometrium. The warning also states that using these products might increase the risk of osteoporosis and bone fractures provera later in life. It may be less expensive than the birth control pills you currently take, depending on your insurance and the type of pill you take. How do I make the shot work best for me? Decrease in Bone Mineral Density Studies in pre-menopausal women show that medroxyprogesterone acetate given as 150 mg intramuscularly every three months reduces serum estrogen levels and is associated with loss of bone mineral density (BMD).

Depo provera side effects

Hepatic Dysfunction Monitor patients for hepatic dysfunction side periodically and temporarily interrupt Depo-Provera Sterile Aqueous Suspension use if the patient develops hepatic dysfunction. If you notice other effects effects not listed above, contact your provera doctor or pharmacist. Skegg DC, Noonan EA, Paul C, Spears GF, Meirik O, side Thomas DB "Depot medroxyprogesterone acetate depo and breast cancer." jama 273 (1995. After stopping Depo-Provera, it might take 10 months or more before you begin ovulating again. Depo-Provera must not be used during pregnancy. Tell your doctor if you wish to become pregnant in the near future. Medroxyprogesterone acetate depo at high doses is an anti-fertility drug and return to ovulation and fertility may be delayed after stopping treatment. Leiman G "Depo-medroxyprogesterone acetate as a contraceptive agent: its effect on weight and blood pressure." Am J Obstet Gynecol 114 (1972. Dosage AND administration, the suspension is intended for intramuscular administration only, rotating the sites effects with every injection. Depending on your start date, your health care provider might recommend that you use a backup method effects of birth control depo for seven days after your first injection. Birth Control side Slideshow Pictures, think You Know Birth Control? They can include: Change in the menstrual cycle is the most common side effect. Teichmann AT, Wander HE, Cremer P,. Farag NH, provera Nelesen RA, Parry BL, Loredo JS, Dimsdale JE, Mills PJ "Autonomic and cardiovascular function in postmenopausal women: The effects of estrogen versus combination therapy." Am J Obstet Gynecol 186(5 Pt 1) (2002. Depo-Provera starts to work as birth control immediately after the first shot, if you get it within the first 5 days of your menstrual period. Clinical experience has side not identified differences in safety or effectiveness between elderly and younger patients. Some people may get annoying side effects while using the birth control shot, but many of them usually go away after 2 or 3 months. Chilvers C "Breast cancer effects and depot-medroxyprogesterone acetate - a review." Contraception 49 (1994 211-22 Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances). (Use a condom for safer sex.) WebMD Medical Reference Reviewed by Kecia Gaither, MD, MPH on July 17, 2017 Sources sources: FamilyDoctor. Renal Impairment The effect of renal impairment on depo-provera pharmacokinetics has not been depo studied. Cundy T, Farquhar CM, Cornish J, Reid IR "Short-term effects of high dose oral medroxyprogesterone acetate on bone density in premenopausal women." J Clin Endocrinol Metab 81 (1996. The following adverse reactions have been observed in patients receiving estrogen-progestin combination drugs: rise in blood pressure in susceptible individuals premenstrual syndrome changes in libido changes in appetite cystitis-like syndrome headache nervousness fatigue backache hirsutism loss of scalp hair erythema multiforma. Increased bone density, if you dont want to get pregnant right away, go see depo a doctor or nurse before your last shot wears off. Effects On The Hypothalmic-Pituitary-Adrenal Axis Some patients receiving medroxyprogesterone acetate may exhibit provera suppressed adrenal function.

Depo provera injection

Immediately after injection provera of injection 150 mg/ml MPA, plasma depo levels were.7.3 nmol/l. For this provera reason, diabetic patients should provera be injection carefully observed while receiving such therapy. Table 3 Adverse Reactions Reported during Post-Marketing Experience Body System Adverse Reactions Body as a Whole Chest pain, Allergic reactions including angioedema, Fever, Injection site abscess, Injection site infection, Injection site nodule/lump, Injection site pain/tenderness, Injection site persistent atrophy/indentation/dimpling, Injection-site reaction, Lipodystrophy. When you stop using Depo-Provera CI your menstrual period will usually, in time, return to its normal cycle. You depo may report side effects to FDA at 1- 800-FDA-1088. The injection use of depo-provera Sterile Aqueous Suspension may, due to its cortisol-like glucocorticoid activity, also produce Cushingoid symptoms such as weight gain, edema/fluid retention, and facial swelling. 5.2 Pharmacokinetic properties Parenteral medroxyprogesterone acetate (MPA) is a long acting progestational steroid. In case of undiagnosed, persistent or recurrent abnormal vaginal bleeding, appropriate measures should be depo conducted to rule out malignancy. Whether this will provide injection protection from endometrial carcinoma has not been depo clearly established. Menstrual Irregularity: The administration of Depo-Provera usually causes disruption of the normal menstrual cycle. If weight is up more than 10 or BP is 130/ 90, refer for clinician evaluation. After stopping use of medroxyprogesterone acetate injection (150 mg IM BMD increased towards baseline injection values during the post-therapy period. Change in normal menstrual cycle. At least 11 metabolites have been reported. Call your doctor for medical advice about side effects. If you miss 1 or 2 depo periods and think you might be pregnant, see your healthcare provider as soon as possible. The site of injection should be cleansed using standard methods prior to administration of the injection. Review STI risk reduction as indicated. The decrease in calcium in your bones is of most concern if you are a teenager or have the following problems: bone disease an eating disorder (anorexia nervosa) a strong family history of osteoporosis you take. Psychiatric Disorders: Patients with a history of endogenous depression should be carefully monitored. How should I take Depo-Provera CI? What are the disadvantages? No hair growth/alopecia (1.1 rash (1.1 urogenital. The decline in BMD was more pronounced during the first two years of use, with smaller declines in subsequent years. The use of Depo-Provera appears to be associated with a 15-20 reduction in serum high injection density lipoprotein (HDL) cholesterol levels which may protect women from cardiovascular disease. Depo-Provera CI may be given at other times than those listed above, but you will likely need to have a pregnancy provera test first to show that you are not pregnant. Depo-Provera is a long-term contraceptive agent suitable for use in women who have been appropriately counselled concerning the likelihood of menstrual disturbance and the potential for a delay in return to full fertility. When used correctly only 3 in 1,000 women will get pregnant. Follow-Up injection More than 14 weeks (98 days) from previous injection : With history of unprotected intercourse after 14 weeks, offer emergency depo contraception if appropriate. See the end of this leaflet for a complete list of ingredients in Depo-Provera. No urine pregnancy testing is necessary after the second visit provera if seen within 14 weeks of prior injection. Two weeks later, levels were.8.8 nmol/l. Unusually heavy or continuous bleeding is not a usual effect of Depo-Provera CI and if this happens you should see your healthcare provider right away. How effective is Depo-Provera? Depo-provera users should be warned of the possibility of decreased efficacy with the use of this or any related drugs. Lasts for 12 weeks. Long-term co-administration of oestrogen is not recommended. Some patients may complain of premenstrual-type depression while on Depo-Provera therapy. Depo Provera is a contraceptive injection containing progestogen. Cancer Risks: Long-term case-controlled surveillance of Depo-Provera users found no overall increased risk of ovarian, liver, or cervical cancer and a prolonged, protective effect of reducing the risk of endometrial cancer in the population of users. Pregnancy Teratogenic Effects It is not known whether medroxyprogesterone acetate can cause fetal harm when administered to a pregnant woman. A longer duration of treatment was associated with a slower rate of BMD recovery. Women who are planning a pregnancy in the next few months may prefer to use a different type of contraceptive.

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